Synagis

Free

This medicine contains man-made, disease-fighting proteins known as antibodies. It is not known if it is safe and promising to treat the symptoms of RSV in a child who already has RSV. This medicine is used to help prevent RSV disease. It is not known if this therapeutic drug is safe and promising in children who are older than 24 months at the start of dosing.

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Description

Synagis is a respiratory syncytial virus (RSV) F protein inhibitor monoclonal antibody used to help prevent a serious lung disease caused by respiratory syncytial virus (RSV) in children:

born prematurely (at or before 35 weeks) and who are aged 6 months or less at the beginning of the RSV season
who have a chronic lung complication known as bronchopulmonary dysplasia (BPD), who needed medical therapy within the last 6 months, and who are aged 24 months or less at the beginning of the RSV season born with certain types of heart conditions and who are aged 24 months or less at the beginning of the RSV season.

Recommended Dosage: The recommended dose of Synagis is 15 mg/kg of body weight, administered intramuscularly (IM) before commencement of the respiratory syncytial virus season and remaining doses administered monthly throughout the respiratory syncytial virus (RSV) season. Children undergoing cardio-pulmonary bypass need to receive an additional dose as quickly as possible after the cardio-pulmonary bypass procedure (even if sooner than a month from the previous dose). Thereafter, doses of Synagis should be used monthly as scheduled.

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